drive up the wall; go on someone's nerves
"The constant humming of that old refrigerator began to madden me after just a few hours."
To make angry.
"The rude comment from the referee maddened the entire home crowd."
A surname, from Irish​.
"The Maddens have lived in that valley since the late 1700s."
Madden is a compound word formed from mad and the suffix -en. It was first used to mean "to make someone insane," directly combining its parts to describe the act of driving another person into a state of madness.