street that serves as a principal thoroughfare for traffic in a town
any small town (or the people who inhabit it); generally used to represent parochialism and materialism (after a novel by Sinclair Lewis)
"Main Street will never vote for a liberal politician"
the principal street of a town, but not necessarily named "Main Street" (qv); there can be more than one main street in some towns.
The generic street name (and often the official name) of the primary retail street of a village, town, or small city in the United States, Canada, Ireland, some parts of Scotland and also in some countries in central Europe.