A (small) island, compare with islet.
"The old manuscript lists 'isle' as an obsolete spelling of aisle, even though it likely referred to a walkway in a church rather than a small island."
Obsolete spelling of aisle
"The lighthouse stood on a small rocky isle in the middle of the ocean."
A city in Minnesota.
"The residents of Isle visited their local park to celebrate Independence Day."
The word "isle" entered English through the Norman conquest via Old French and originally meant a small piece of land surrounded by water. Although it shares a root with the Latin word insula, it developed as a distinct term separate from the native English word "island."