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Sickle cell anaemia

Related Terms:

red blood cell sickle disease oxygen people africa affect origin anaemia infarction capillary haemoglobin ischaemia shape

Noun

Definition: A severe hereditary form of anaemia, mainly affecting people of African origin, in which mutated haemoglobin distorts red blood cells into a crescent shape, causing the cells to become stuck in capillaries. Downstream tissues are thus deprived of oxygen causing ischaemia and infarction.

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