an impairment of health or a condition of abnormal functioning
"The doctor explained that his recent fatigue was likely just a temporary disease caused by overworking rather than a chronic illness."
An abnormal condition of a human, animal or plant that causes discomfort or dysfunction; distinct from injury insofar as the latter is usually instantaneously acquired.
"The farmer inspected his crops closely to determine if the yellowing leaves were caused by an insect bite or a spreading disease like blight."
In plain English: A disease is a problem that makes your body not work right and causes you to feel sick.
"The doctor diagnosed the patient with a common viral disease."
Usage: Use "disease" to describe an underlying illness or medical condition that develops over time rather than an immediate physical injury. It refers specifically to disorders affecting the body's normal functions, such as diabetes or the flu, rather than wounds caused by accidents.
To cause unease; to annoy, irritate.
"The constant noise from the construction site near my window began to dise me after just a few hours."
In plain English: To disease something is to make it sick or unhealthy.
"The disease began to spread rapidly through the camp."
Usage: The verb form of disease is archaic and rarely used in modern English; instead, use words like annoy or disturb to mean causing unease. Most contemporary speakers should avoid this usage entirely as it sounds unnatural and outdated.
The word "disease" entered English from Anglo-Norman and Old French, where it originally meant a state of being un-eased or uncomfortable. Although the components "dis-" and "ease" suggest an opposite of comfort, this term replaced earlier native words for sickness like adle and cothe.