a very long fly ball
"The batter hit a blast over the outfield fence, sending the crowd into an uproar."
an explosion (as of dynamite)
"The soldiers were caught in a sudden blast from the enemy's dynamite."
A violent gust of wind.
"The bioinformatics team used a blast to identify regions of similarity between the newly sequenced gene and known protein databases."
An immature or undifferentiated cell (e.g., lymphoblast, myeloblast).
An algorithm which compares similarities between sequences of nucleotides in nucleic acids or of amino acids in proteins.
In plain English: A BLAST is a computer tool used to find similar genetic code or protein structures.
"Bioinformaticians use a sequence blast to identify related genes across different species."
Usage: Blast (as in BLASTn, BLASTp) refers specifically to a bioinformatic tool used to search sequence databases for similar matches; it's not just any explosion or enjoyable experience. Use "BLAST" when discussing bioinformatics and sequence alignment.
shatter as if by explosion
"The sudden shockwave from the nearby dynamite blast shattered every window in the building."
shrivel or wither or mature imperfectly
"The frosty night caused the tender buds to blast, leaving them shriveled and brown before they could open."
To make an impression on, by making a loud blast or din.
"The researcher decided to blast the new gene sequence against the database to find potential matches."
To run a nucleotide sequence (for nucleic acids) or an amino acid sequence (for proteins) through a BLAST (Basic Local Alignment Search Tool).
Alternative letter-case form of blast (to run a sequence through BLAST)
In plain English: To blast means to use a computer program to compare a DNA or protein sequence against others to find similar matches.
"Scientists blast the DNA sequences to find similar genes in other organisms."
Usage: When referring to bioinformatics, "blast" means to perform a search using the Basic Local Alignment Search Tool (BLAST) algorithm to compare a query sequence against a database. It's typically used in contexts like "I need to blast this DNA sequence."
To show displeasure or disappointment; damn
"I blast when my favorite team loses in overtime."
The word "blast" comes from Old English blǣst, which originally meant a strong blowing of wind or an explosion caused by air pressure. It traveled into modern usage with this same core meaning related to forceful gusts and sudden outbursts.