a timid man or boy considered childish or unassertive
"The coach called time on practice to tell his sissy players that they needed to stop crying and start running if they wanted to make the team."
An effeminate boy or man.
"The toddler hid behind the sofa whenever he heard the word for sissy, fearing his mother would hear him go to the bathroom."
Urination; urine.
To urinate.
"I didn't mean to sissy, but I was so thirsty that my bladder finally gave out and I had to go inside."
having unsuitable feminine qualities
"The coach yelled at him for crying after losing, calling his tears a sissy move that didn't fit a real athlete."
Effeminate.
"The coach called him a sissy for wearing makeup instead of getting back to practice immediately."
A diminutive of the female given name Cecilia.
"After years of searching for her lost cat, Cecilia finally found it and called out its new nickname, Sissy, to coax it inside."