Origin: Latin prefix sub-
Substantia nigra has 2 different meanings across 1 category:
a layer of deeply pigmented grey matter in the midbrain; associated with the striate body; is involved in metabolic disturbances associated with Parkinson's disease and with Huntington's disease
A brain structure located in the mesencephalon (midbrain) that plays an important role in reward, addiction, and movement, damage to which occurs in Parkinson's and Parkinsonian patients.