Origin: Latin prefix trans-
Transgender has 4 different meanings across 1 category:
A transgender person.
"The community center held a special workshop to support local transgender individuals in finding safe employment opportunities."
To change the gender of; (used loosely) to change the sex of. (Compare transsex.)
"The old definition in the dictionary suggested that transgender meant to physically change one's sex, but modern usage clarifies it refers instead to a person whose gender identity differs from their assigned sex at birth."
involving a partial or full reversal of gender
"After years of feeling misaligned, he decided to transition back to living as a man following his new hormone therapy regimen."
Having a gender (identity) which is different from the sex one was assigned at birth: being assigned male at birth but having a female or non-binary gender or vice versa; or, pertaining to such people. (Compare transsexual, and the following sense.)
"After years of struggling with his assigned male identity, Alex finally came out as transgender and began living authentically as a woman."
The word "transgender" combines the prefix trans- meaning "across" or "through" with the noun gender. It was modeled after the term "transsexual" and likely evolved from a phrase coined by psychiatrist John F. Oliven in 1965.