a bundle of myelinated nerve fibers following a path through the brain
"Damage to the corticospinal pathway can result in paralysis below the level of injury."
A footpath or other path or track.
"The hikers followed the narrow pathway through the dense forest to reach the summit."
In plain English: A pathway is an open way through which something can move, such as a road for walking or a series of steps leading to success.
"The children played on the stone pathway that led to the garden."
The word pathway comes from the Middle English combination of path and way. It entered modern usage as a straightforward compound meaning an open road or track for walking.