Run down has 8 different meanings across 1 category:
Verb
trace
"We are running down a few tips"
move downward
"The water ran down"
injure or kill by knocking (someone or something) down and passing over the body, as with a vehicle
use up all one's strength and energy and stop working
"At the end of the march, I pooped out"
examine hastily
"She scanned the newspaper headlines while waiting for the taxi"
deplete
"exhaust one's savings"
"We quickly played out our strength"
pursue until captured
"They ran down the fugitive"
To hit someone with a car or other vehicle and injure or kill them.