An edifice or building.
"The ancient stone fabric of the cathedral has survived centuries of storms and wars."
In plain English: Fabric is the cloth material that you use to make clothes and other things.
"She chose a soft cotton fabric for her new summer dress."
Usage: Fabric refers to material used for making clothes or other goods, not an edifice or building. Use this word when describing textiles like cotton or wool, whereas structures are described with words like structure or edifice.
The word "fabric" comes from the French fabrique, which originally meant a workshop or trade rather than just cloth. It traces back to the Latin fabrica ("workshop") and faber ("artisan"), reflecting its early sense of something constructed by human hands.